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Ketoconazole 99% 65277-42-1 Antifungal material

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Ketoconazole / CAS:65277-42-1/Anti fungual/Antimycotic/APIs/Pharmaceutical 

1.Synonyms: cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine

2.Molecular Formula: C26H28Cl2N4O4

3.Molecular Weight: 531.44

4.CAS: 65277-42-1

5.EINECS: 265-667-4

6.Melting point: 146 ºC

7.Standard: USP33

8.Type: Antibiotic and Antimicrobial Agents

9.Appearance: white or almost white crystalline powder

Ketoconazole is a synthetic antifungal drug used to prevent and treat fungal skin infections, especially in immunocompromised patients such as those with AIDS or those on chemotherapy. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet.

Analysis of sheet

Main Function

1. Systemic fungal infections, such as systemic candidiasis, Candida, under spherical spore bacteria disease,  histoplasma fungus disease, ball, Bud spore bacteria disease bacteria.

 2. By skin fungi and (or) yeast caused of skin, and hair and refers to (toe) of infection (skin fungi disease, and methyl  Tinea, and beads bacteria sex methyl week inflammatory, and spotted Tinea, and scalp bran rash Tinea sex hair  follicles inflammatory and the chronic skin mucosa beads bacteria disease,), dang local treatment invalid or due to  infection parts, and area and the depth, factors cannot medication Shi, available the products treatment.

 3. Local treatment of chronic, recurrent vaginal candidiasis.

  4. For prophylaxis because of reduced immune function (genetic and caused by disease or drugs) and prone to    fungal infections in patients.


 Application


This product is an imidazole antifungal drug. For skin fungi, yeasts (Candida, pityrosporum bacteria genus, ball intends to Saccharomyces, Cryptococcus), duplex fungi or Eumycetes bacteriostatic and bactericidal action; apart from the entomophthorales,, the product of the Aspergillus, Shen sporotrichum, some dark Spore, Mucor are lower. The main mechanism for highly selective disturbance of activity of fungal cytochrome P-450, thus inhibiting cell membrane ergosterol biosynthesis in fungi.


This product is an imidazole antifungal drug. For skin fungi, yeasts (Candida, pityrosporum bacteria genus, ball intends to Saccharomyces, Cryptococcus), duplex fungi or Eumycetes bacteriostatic and bactericidal action; apart from the entomophthorales,, the product of the Aspergillus, Shen sporotrichum, some dark Spore, Mucor are lower. The main mechanism for highly selective disturbance of activity of fungal cytochrome P-450, thus inhibiting cell membrane ergosterol biosynthesis in fungi.